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Xerostomia and the Geriatric Patient

Identifieur interne : 002170 ( Main/Exploration ); précédent : 002169; suivant : 002171

Xerostomia and the Geriatric Patient

Auteurs : Jonathan A. Ship ; Stanley R. Pillemer [États-Unis] ; Bruce J. Baum [États-Unis]

Source :

RBID : ISTEX:C9F2CCDA9BF69E8971474B88B644DB22C6B4F6EF

English descriptors

Abstract

Saliva is essential for the preservation of oral‐pharyngeal health, and disorders of salivary physiology are associated with numerous oral and pharyngeal problems, particularly in older people. Although salivary function is remarkably intact in healthy aging, medical problems, medications, and head and neck radiotherapy can cause salivary dysfunction and complaints of xerostomia among older people. Sjögren's syndrome, an autoimmune exocrinopathy, is the most common medical disease associated with salivary dysfunction. Medications with anticholinergic side effects will impair salivary output, and head and neck radiotherapy for cancer will cause permanent destruction of salivary glands. Treatments for salivary problems are based upon establishing a diagnosis, protecting oral and pharyngeal health, stimulating remaining glands, and replacing lost salivary fluids.

Url:
DOI: 10.1046/j.1532-5415.2002.50123.x


Affiliations:


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Le document en format XML

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<term>Acinar</term>
<term>Acinar cell</term>
<term>Acinar cells</term>
<term>Adverse effects</term>
<term>Angular cheilitis</term>
<term>Anticholinergic</term>
<term>Anticholinergic effects</term>
<term>Anticholinergic side effects</term>
<term>Arch intern</term>
<term>Arthritis rheumatol</term>
<term>Artificial saliva</term>
<term>Autoantibody</term>
<term>Autoimmune exocrinopathy</term>
<term>Baum</term>
<term>Biol</term>
<term>Cell proliferation</term>
<term>Clin</term>
<term>Clin exper rheumatol</term>
<term>Comm dent</term>
<term>Common cause</term>
<term>Curr opin rheumatol</term>
<term>Current therapies</term>
<term>Cytotoxic agents</term>
<term>Dent</term>
<term>Dent assoc</term>
<term>Diagnostic criteria</term>
<term>Dose delivery techniques</term>
<term>Ductal system</term>
<term>Dysfunction</term>
<term>Effective treatment</term>
<term>Eisbruch</term>
<term>Elderly patients</term>
<term>European classification criteria</term>
<term>Flow rate</term>
<term>Flow rates</term>
<term>Fluid secretion</term>
<term>Gastrointestinal tracts</term>
<term>Geriatric</term>
<term>Geriatric patient</term>
<term>Geriatric population</term>
<term>Gland</term>
<term>Gland biopsy</term>
<term>Gland dysfunction</term>
<term>Gland function</term>
<term>Glandular fluid production</term>
<term>Host disease</term>
<term>Human parotid saliva</term>
<term>Hypofunction</term>
<term>Inhibitor</term>
<term>Jag</term>
<term>Keratoconjunctivitis sicca</term>
<term>Lacrimal glands</term>
<term>Lymphoma</term>
<term>Medical problems</term>
<term>Medication</term>
<term>Medicationinduced xerostomia</term>
<term>Memory loss</term>
<term>Much research</term>
<term>Multidisciplinary approach</term>
<term>Muscarinic</term>
<term>Muscarinic receptors</term>
<term>Neck cancer</term>
<term>Neck cancer patients</term>
<term>Neck cancers</term>
<term>Neck irradiation</term>
<term>Neck radiation</term>
<term>Neck radiotherapy</term>
<term>Objective evidence</term>
<term>Ocular symptoms</term>
<term>Older adults</term>
<term>Older people</term>
<term>Olmsted county</term>
<term>Oncol</term>
<term>Oncol biol phys</term>
<term>Oral biol</term>
<term>Oral candidiasis</term>
<term>Oral mucosal surfaces</term>
<term>Oral path</term>
<term>Oral pilocarpine</term>
<term>Oral surg</term>
<term>Osmotic gradient</term>
<term>Parotid</term>
<term>Parotid gland</term>
<term>Parotid saliva</term>
<term>Phys</term>
<term>Pilocarpine</term>
<term>Positive response</term>
<term>Positive result</term>
<term>Prevalence</term>
<term>Primary syndrome</term>
<term>Protein exocytosis</term>
<term>Protein secretion</term>
<term>Radiol endo meurman</term>
<term>Radiotherapy</term>
<term>Receptor</term>
<term>Rheumatoid factor</term>
<term>Rheumatol</term>
<term>Saliva</term>
<term>Saliva secretion</term>
<term>Salivary</term>
<term>Salivary dysfunction</term>
<term>Salivary flow</term>
<term>Salivary flow rate</term>
<term>Salivary flow rates</term>
<term>Salivary function</term>
<term>Salivary gland</term>
<term>Salivary gland dysfunction</term>
<term>Salivary gland function</term>
<term>Salivary gland hypofunction</term>
<term>Salivary gland involvement</term>
<term>Salivary gland secretion</term>
<term>Salivary glands</term>
<term>Salivary hypofunction</term>
<term>Salivary output</term>
<term>Salivary proteins</term>
<term>Salivary secretion</term>
<term>Salivary secretions</term>
<term>Secretion</term>
<term>Serous</term>
<term>Serous acinar cells</term>
<term>Sicca syndrome</term>
<term>Sjogren syndrome</term>
<term>Sodium chloride</term>
<term>Spec care dent</term>
<term>Special reference</term>
<term>Submandibular</term>
<term>Submandibular gland</term>
<term>Subsequent generation</term>
<term>Surg</term>
<term>Syndrome</term>
<term>Systemic diseases</term>
<term>Systemic lupus erythematosus</term>
<term>Systemic manifestations</term>
<term>Thyroid gland</term>
<term>Treatment planning</term>
<term>Tricyclic antidepressants</term>
<term>Whole saliva</term>
<term>Xerostomia</term>
<term>Xerostomia clinic</term>
<term>York university college</term>
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<div type="abstract" xml:lang="en">Saliva is essential for the preservation of oral‐pharyngeal health, and disorders of salivary physiology are associated with numerous oral and pharyngeal problems, particularly in older people. Although salivary function is remarkably intact in healthy aging, medical problems, medications, and head and neck radiotherapy can cause salivary dysfunction and complaints of xerostomia among older people. Sjögren's syndrome, an autoimmune exocrinopathy, is the most common medical disease associated with salivary dysfunction. Medications with anticholinergic side effects will impair salivary output, and head and neck radiotherapy for cancer will cause permanent destruction of salivary glands. Treatments for salivary problems are based upon establishing a diagnosis, protecting oral and pharyngeal health, stimulating remaining glands, and replacing lost salivary fluids.</div>
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